11 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... are asthma, allergy ... organ-specific signs ... , skin or esophageal ... #Differential #diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
proximally to arms ... Hepatic: PBC (primary ... biliary cholangitis ... #signs #symptoms ... #testing #workup
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... failure PBC Signs ... and Symptoms: ... Examination: • Skin ... #workup #hepatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... #Rash #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... or secondary hemostasis ... deficiency Work ... cryoglobulins • Skin
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... #dermatology #oncology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Rash, pink ... exposure to or symptoms ... of primary or secondary ... granuIomas on skin ... #Tertiary #Diagnosis
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... • Acne • If secondary ... , oral cavity) Caused ... not a feature of primary ... #signs #symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
+ distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... Leukemia #Hematology #Oncology ... #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... loss, arthralgia, arm ... bruits, asymmetric arm ... , mucositis • Rash ... tract, and often causes