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rheumatology acidosis bruising cryofibrinogenemia elevation erythematosus extravascular hemolysis hemolytic hodgkins lactate lactic lymphoma macrophage oncology pediatrics peds thrombocytopenia typea typeb
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... thrombocytopenic purpura ... usually IgG) (e.g. lupus ... #Causes #differential ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... • Systemic lupus ... [SLE], AOSD) • ... #Syndrome #Diagnosis ... #Management #Hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... (systemic lupus ... Congenital heart disease ... pediatrics #diagnosis ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Diagnosis: • ANCA-associated ... Chronic B-cell activation ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease Differential ... Diagnosis: Systemic ... , such as systemic ... #diagnosis #rheumatology ... #classification
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... Skin necrosis • Purpura ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
disease states ... of Circulatory System ... - Compartment syndrome ... 30mmHg) - Severe anemia ... #Diagnosis #causes
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