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oncology differential mds myelodysplastic acidosis activation chronic cll elevation extravascular hemolysis hemolytic infectiousdiseases intravascular leukemia lymphocytic macrophage mas mycobacteria myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... - Drugs (Beta lactam ... #hematology #anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... propylthiouracil) - β-lactam ... anemia Treatment ... #hematology #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The most common ... presentations and disease ... - Compartment syndrome ... #typeb #classification
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Syndrome - Diagnosis ... • Dyspnea - Common ... #syndrome #diagnosis ... #management #treatment ... #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Most common cytopenia ... • Anemia • Aplastic ... Myeloproliferative Disease ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... #Diagnosis #Management ... #Hematology #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... other RGM • Plastic ... Bone Marrow - Anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... • Neutropenia, anemia ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
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