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rheumatology behcet bruising cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology dyspnea hemoptysis hemostasis nonpalpable palpable prs purpura renal signs sjogrens sob symptoms syndromes
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Asthma - COPD ... HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #diagnosis #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Vasculitis ... Leukocytoclastic vasculitis ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Mechanisms (Principally Vasculitis ... • IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... vasculitis
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... carcinoid, Mets), COPD ... Autoimmune: ANCA-Assoc vasculitis ... #Diagnosis #pulmonary ... #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , such as SLE, atherosclerotic ... tract, and often causes ... #Differential #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... MCC-small vessel vasculitis ... ) Differential Diagnosis ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... Goodpasture's cause ... #differential # ... diagnosis #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... malignancies, vasculitis ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Diagnosis #Management
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