14 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Asthma - COPD ... HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #diagnosis #causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Vasculitis ... Leukocytoclastic vasculitis ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... in 24h Airway disease ... Autoimmune: ANCA-Assoc vasculitis ... Diagnosis #pulmonary ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology # ... classification
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... ): SS, SC, SE, Sβ ... cardiac valve, vasculitis ... elliptocytosis, autoimmune hemolysis ... #workup #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , such as SLE, atherosclerotic ... tract, and often causes ... #Differential #Diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Mechanisms (Principally Vasculitis ... • IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... vasculitis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... MCC-small vessel vasculitis ... ) Differential Diagnosis ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... palpable purpura 2/2 vasculitis ... #differential # ... diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... malignancies, vasculitis ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... hematology