12 results
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
' per se. ... indicates unknown cause ... and interstitial ... #Diagnosis #Radiology ... #Pulmonary #CTChest
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... due to lung disease ... disease Interstitial ... lung disease Other ... #Causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
physical exam findings ... likely it will be clinically ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... findings (ANA, ... Classification: ... Features: Lungs ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Features: HEENT ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Based on the images alone, it is usually not possible to determine the cause of the
non-pulmonary findings ... this is nodular interstitial ... lung disease, that ... #Clinical #Diagnosis ... #Radiology #CXR
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... Disease: Clinical ... Lung Disease: ... Imaging, high res CT
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... discrepancies Findings ... SLE) • Urinalysis ... #rheumatology # ... classification
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
of intrinsic lung ... disease Caused ... shunt (Type 2) Clinical ... dilation - Positive findings ... resolution of HPS features