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management vasculitis infectiousdiseases activation aids antibodies antinuclear aortitis cryoglobulinemia cryoglobulins cvid dermatologic gpa hiv hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma macrophage
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Diagnosis: • ANCA-associated ... Kidney disease common ... #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... erythematosus ( ... SLE), Sarcoidosis ... #Diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Liver diseases and ... lung disease (GLILD ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... to exclude are infections ... SLE) • Urinalysis ... #diagnosis #rheumatology ... #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, lung ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... (e.g. systemic lupus ... erythematosus ( ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... Nodosa: • PAN most commonly ... ischemia • Skin: Erythematous ... often causes arthritis ... #Diagnosis #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... Disease: Clinical ... Imaging, high res CT ... #differential #
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