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infectiousdiseases lupus systemic vasculitis antinuclear autoantibodies autoimmune classification hiv management mimickers mycobacteria mycoses myopathy myositis nontuberculous ntm patterns vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... , dermatomyositis ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... Auto-Antibodies ... Diagnosis and Lupus ... #signs #symptoms ... #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... lung disease Malignancy ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
purpura: strong sign ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
lung infections ... Disease: Clinical ... • Clinical (Symptoms ... Imaging, high res CT ... #differential #
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... • CT: Halo sign ... Constitutional symptoms ... #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms ... • Rheumatologic ... stain of clinical ... yeast • At risk: AIDS ... pulmonary infection
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