9 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Myositis, Mixed ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Auto-Antibodies ... : - ANA 95-100% ... Diagnosis and Lupus ... #signs #symptoms ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... , dermatomyositis ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... lung disease Malignancy ... lung disease • ... lung disease • ... #Myopathy #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... MALT Lymphoma • Lung ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammatory lesions-interstitial ... Presentation - Systemic Symptoms ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Disease: Clinical ... • Clinical (Symptoms ... Imaging, high res CT ... #diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
CT: Halo sign ... Constitutional symptoms ... Infections #HIV #AIDS ... #pulmonary #differential ... #diagnosis #infectiousdiseases
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... • Progressive symptoms ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology