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differential cardiology infectiousdiseases activation ana antibodies classification conditions cvid erythematosus extrarticular fungal hodgkins hypogammaglobulinemia immunodeficiency immunology joint lupus lymphoma macrophage
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... syndrome - SLE ... #differential #diagnosis ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... common • Antihistone ... #Rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... regurgitation • Autoimmune ... (SLE Libman Sacks ... Cerebral > Splenic, pulmonary ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... erythematosus [SLE ... ], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... regurgitation • Autoimmune ... (SLE Libman Sacks ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... , such as SLE, atherosclerotic ... Nodosa: • PAN most commonly ... inflammatory lesions - interstitial ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... classification #hematology ... #oncology #management
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