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differential activetb hematology infectiousdiseases latenttb tb aids common cvid hemophagocytic hlh hypogammaglobulinemia immune immunodeficiency immunology iris lymphohistiocytosis mas mycobacteria nontuberculous
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
abscess Primary ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
abscess Primary ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... #TB #Diagnosis ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
of macrophages ... production of pro-inflammatory ... : SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung Abscess - Clinical ... Abscess Diagnosis ... #Abscess #pulmonary ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... rash) • Heart, lung ... erythematosus [SLE ... #Activation #Syndrome ... #Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... #diagnosis #management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... : • Syndrome of ... Disease: Clinical ... Lung Disease: ... Imaging, high res CT
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... in HIV • Lung ... #Infections #HIV ... #AIDS #pulmonary
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
hematuria) • Inflammatory ... confirm DAH, r/o infection ... sparing of the lung ... hemosiderin laden macrophages ... #management #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
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