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management classification erythematosus infectiousdiseases systemic vasculitis aids antinuclear autoantibodies autoimmune bronchiectasis cvid druginduced hiv hodgkins immunodeficiency immunology lymphoma mimickers mycobacteria
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... #immunology #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... Auto-Antibodies ... Diagnosis and Lupus ... Other auto-immune, Infectious ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... : • Symptoms limited ... Kidney disease common ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
ON CT? ... ) WHAT ARE COMMON ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Disease: Clinical ... • Clinical (Symptoms ... Imaging, high res CT ... #differential #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... lung disease Malignancy ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
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