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differential management erythematosus systemic table ana antinuclear associations autoimmune classification connectivetissuediseases ctild druginduced fungal ild infectiousdiseases lungdisease mimickers mycoses myopathy
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... rheumatoid arthritis SLE ... : systemic lupus ... #Table #Pulmonary ... #Rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... Auto-Antibodies ... #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... • Anti-Ro/SSA autoantibodies ... fibromyalgia) • Infections ... : • Symptoms limited
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
to exclude are infections ... Presentation - Systemic Symptoms ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... lung disease Malignancy ... lung disease • ... lung disease • ... Mechanic's hands Autoantibodies
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... change in the lungs ... nails, bronchi, lungs
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