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differential infectiousdiseases amiodarone common cvid erythematosus extrarticular fungal hematology hypogammaglobulinemia immunodeficiency induced lupus mycobacteria mycoses nontuberculous ntm pain systemic toxicity
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and Other Conditions ... Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... granulomatous conditions ... #hematology #diagnosis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Predisposing conditions ... Disease: Clinical ... Lung Disease: ... • Clinical (Symptoms ... Imaging, high res CT
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
hypersensitivity/immunologic ... gradually with symptoms ... failure - Infectious ... Exclusion of other ILDs ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... fibromyalgia) • Infections ... Arthritis: • Joint ... Induced Lupus: • Symptoms ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... or as primary condition ... • Progressive symptoms ... inflammatory lesions - interstitial ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... muscle aches, joint ... yeast • At risk: AIDS ... #Management #Infections
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