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differential classification joint syndrome vasculitis activation ana antibodies antinuclear arthritis common cvid extrarticular hodgkins hypogammaglobulinemia immunodeficiency immunology infectiousdiseases lupus lymphoma
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... constitutional symptoms ... Rheumatologic Disease ... arthritis • SLE ... #MSK #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Predisposing conditions ... Hematologic malignancy ... Disease: Clinical ... • Clinical (Symptoms ... Imaging, high res CT
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... [SLE], AOSD) • ... Infection (eg, ... #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammatory lesions-interstitial ... to exclude are infections ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... or as primary condition ... ischemia • Skin: Erythematous ... inflammatory lesions - interstitial ... #Rheumatology
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