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differential syndrome infectiousdiseases activation amiodarone fungal hematology hepatology hepatopulmonary hlh induced lymphohistiocytosis macrophage mas mycobacteria mycoses nontuberculous ntm prs renal
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Summary Lung ... Lung Abscess - Clinical ... #Abscess #pulmonary ... #management #treatment
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Disease: Clinical ... Lung Disease: ... • Clinical (Symptoms ... Imaging, high res CT
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... rash) • Heart, lung ... erythematosus [SLE ... ], AOSD) • Infection ... #Management #Hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... confirm DAH, r/o infection ... or serologies + symptoms ... sparing of the lung ... #management #treatment
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Toxicity Summary ... gradually with symptoms ... failure - Infectious ... Exclusion of other ILDs ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Summary A defect ... disease Caused ... shunt (Type 2) Clinical ... resolution of symptoms ... #management #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... #Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... Sinusitis • Brain abscess ... change in the lungs ... #Management #Infections
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