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differential management ana antinuclear erythematosus table associations autoantibodies comparison connectivetissuediseases ctild cvid fungal hematology hypogammaglobulinemia ild immunodeficiency immunology infections lungdisease
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... #Rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Classification: ... common • Antihistone ... #Systemic #Lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... overlap syndromes ... and there is no common ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... MALT Lymphoma • Lung ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
as systemic lupus ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... #rheumatology # ... classification
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hemolytic anemia) • Systemic
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
droppings • Most common ... symptoms • Rheumatologic ... has five major clinical ... change in the lungs ... ) #Mycoses #InfectiousDiseases
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