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differential management infectiousdiseases aids antibodies cd4 classification common conditions cvid evaluation extrarticular hiv hivaids hypogammaglobulinemia immunodeficiency immunology induced joint mycobacteria
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
physical exam findings ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Pleuritic chest ... Characteristic finding ... failure - Infectious ... reticular opacities on chest ... confirmatory findings
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... failure, COPD, Lung ... CXR +/- High res CT ... chest scan), CBC ... Diseases Fellows
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
chest to evaluate ... confirm DAH, r/o infection ... sparing of the lung ... typically seen on chest ... CT
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... - Cough and lung ... • Dyspnea, • Chest ... Lung Disease: ... Imaging, high res CT
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • Pleuritic chest ... Lymphadenopathy, Chest ... breath, Fatigue, Chest ... Pneumonia: • Chest
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
to exclude are infections ... discrepancies Findings ... LFT • ESR • ANA ... SLE) • Urinalysis ... #rheumatology #
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