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differential management aids antibodies antinuclear cd4 classification common conditions cvid evaluation extrarticular fungal hiv hivaids hypogammaglobulinemia immunodeficiency immunology induced joint
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Pleuritic chest ... Characteristic finding ... failure - Infectious ... reticular opacities on chest ... confirmatory findings
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
physical exam findings ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... failure, COPD, Lung ... CXR +/- High res CT ... chest scan), CBC ... Diseases Fellows
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... • Dyspnea, • Chest ... Lung Disease: ... Imaging, high res CT ... #infectiousdiseases
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
chest to evaluate ... confirm DAH, r/o infection ... sparing of the lung ... typically seen on chest ... CT
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • Pleuritic chest ... Lymphadenopathy, Chest ... breath, Fatigue, Chest ... Pneumonia: • Chest
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammatory lesions-interstitial ... to exclude are infections ... discrepancies Findings ... SLE) • Urinalysis ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... aches, joint pain, chest ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
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