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differential management infectiousdiseases abscess aids amiodarone bronchiectasis causes cd4 classification common cvid evaluation hivaids hypogammaglobulinemia immunodeficiency induced mycobacteria nontuberculous ntm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... failure, COPD, Lung ... CXR +/- High res CT ... chest scan), CBC ... Diseases Fellows
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... : Pleuritic chest ... level seen • Chest ... CT Lung Abscess ... until the chest
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Advanced HIV (CD4 ... Hematologic malignancy ... • Dyspnea, • Chest ... Lung Disease: ... Imaging, high res CT
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Loss of weight • Chest ... high-resolution chest ... CT) • Broncho-arterial ... , CCP, ANCA • HIV ... mycobacteria Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
chest to evaluate ... confirm DAH, r/o infection ... sparing of the lung ... typically seen on chest ... #management #treatment
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
hypersensitivity/immunologic ... Pleuritic chest ... Characteristic finding ... failure - Infectious ... reticular opacities on chest
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • Pleuritic chest ... Lymphadenopathy, Chest ... Pneumonia: • Chest ... #Infections #HIV
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammatory lesions-interstitial ... to exclude are infections ... discrepancies Findings ... vasculitis, and SLE ... #rheumatology #
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