5 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... #ANCA #Antineutrophil ... #antibodies #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinuria, rapidly progressing ... often causes arthritis ... LFT • ESR • ANA ... , and SLE) • Urinalysis ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Measurement of antinuclear ... antibodies, antineutrophil ... • Abdominal ultrasound ... #Algorithm #Causes ... #dermatology #physicalexam
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... , INC risk PE, Pulmonary ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management