7 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... #Antinuclear #Antibody ... #antibodies #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Purpura Anti-GBM antibodies ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (ANA) ANA or Anti-NucIear ... Antibody refers ... #Antibodies #ANA ... #patterns #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Measurement of antinuclear ... antibodies, antineutrophil ... • Abdominal ultrasound ... #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and/or pulmonary ... often causes arthritis ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... DDX: • ANCA (Antineutrophil ... cytoplasmic antibody ... classification #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... acidosis • NAGMA • Glomerulonephritis ... Sjogrens #Syndrome #Rheumatology