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differential classification patterns vasculitis algorithm cryoglobulinemia cryoglobulins dermatology disease diseases erythematosus laboratory management petechiae petechial physicalexam rash rheumatic rheumatoid syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... #Antinuclear #Antibody ... #ANCA #Antineutrophil ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... ), Sjogren's Syndrome ... , Interstitial Pulmonary ... #Antibodies #ANA
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... ), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... dermatomyositis, Sjogren ... : • Joint pain ... Serositis Labs: • ANA
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
lesions • Severe pain ... , RA, Sjogren's, ... Measurement of antinuclear ... antibodies, antineutrophil ... • Abdominal ultrasound
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... ) - Antinuclear ... antibody (ANA) test ... antibodies, which ... , a negative ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... DDX: • ANCA (Antineutrophil ... cytoplasmic antibody ... (e.g. systemic lupus ... classification #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... , INC risk PE, Pulmonary ... Arthritis Malignancy ... #Syndrome #Rheumatology
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