9 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Sjogren's ... : Lupus (SLE), Systemic ... Arthritis, Sjögren ... #Antibodies #ANA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... (SLE), Sjogren's ... (SLE), Systemic ... #Antibodies #ANA
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Other Conditions ... Associated with Joint Pain ... • Pulmonary ... #Extrarticular ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... : Systemic rheumatic ... as systemic lupus ... SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid ... arthritis, Sjögren's
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... : • Joint pain ... • (-) ANA + (+ ... #Systemic #Lupus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
lupus erythematosus ... (SLE) - Antinuclear ... antibodies, which ... low back pain) ... #Disease #Rheumatoid
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Vasculitis: • 7%, Cryoglobulinemia ... Arthritis Malignancy ... #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Systemic rheumatic ... as SLE, atherosclerotic ... or as primary condition ... often causes arthritis ... #Rheumatology