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differential ana erythematosus lupus patterns systemic vasculitis autoantibodies classification laboratory management rheumatic rheumatoid sjogrens table testing vasculitides
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Juvenile Idiopathic Arthritis ... ), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... , Interstitial Pulmonary ... #Antibodies #ANA ... #patterns #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- GI tract: abdominal ... Supply gut -> abdominal ... ) pattern: antibodies ... vasculitis, and SLE ... #rheumatology #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... : • ANCA-associated ... Clinical Features ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... ) - Antinuclear ... double-stranded DNA antibodies ... ACE level, CXR, ANCA ... and RF (if clinical
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... , such as SLE, atherosclerotic ... multiplex • GI tract: Abdominal ... gut involvement, abdominal ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... Arthralgia and Arthritis ... #Rheumatology #
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