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differential management autoantibodies bcnie bloodculture classification endocarditis erythematosus fungal infections infective lupus mycoses negative patterns sjogrens systemic table vasculitides vasculitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... , Interstitial Pulmonary ... #Antibodies #ANA ... #patterns #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... : • 10%-15% Pulmonary ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- GI tract: abdominal ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... Assays for antinuclear ... antibodies, rheumatoid ... antiphospholipid syndrome ... exists Infectious Diseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... 3) Abdominal, ... fungal stain of clinical ... ) #Mycoses #InfectiousDiseases
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