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Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... ARUPConsult @ARUPLabs #C1INH ... #Complement #esterase
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Antibody/DAT+ - Complement ... Differential #Diagnosis #Causes
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... of alternative complement ... MPGN without complement
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... HUS (aHUS) - Complement-mediated
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... types #allergy #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... helpful paper complements ... #Differential #Table
Dyspnea - Differential Diagnosis and Presentation #Diagnosis #Differential #Table #Dyspnea #SOB #Causes
#Differential #Table ... #Dyspnea #SOB #Causes
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
conditions all of which cause ... different types/causes ... RenalTubularAcidosis #Features #Table
Causes of Cough and Hemoptysis Acute Inflammation - Laryngitis - Tracheobronchitis - Mycoplasma and
Causes of Cough ... , Chemicals, Gases ... #Differential #Causes ... #Table
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