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diagnosis differential classification genetics iem immunology inbornerrors metabolism neonatology nicu pediatrics peds rheumatology table vasculitis ards clinical criticalcare ctchest disorders
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
Lab patterns seen ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... IEM #Laboratory #Patterns
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... activation -> Complement ... Maculopapular rash #C5C9Deficiency ... #Complement #pathophysiology
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE ... #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... See the lab values ... MetabolicEmergency #Genetics #Pathophysiology ... #Diagnosis #Algorithm
Algorithm for nodular pattern The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following: - Look
Algorithm for nodular ... pattern The algorithm ... often easiest to see ... are visible, the pattern ... #Differential #Algorithm
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... classical pathway (see ... Complement Activation ... Humoral #Immunity #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... involvement, irregular pattern ... Classification #pathophysiology ... #differential #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- (C-ANCA) pattern ... - (P-ANCA) pattern ... against MPO • Complement ... vasculitis, and SLE
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
, and we often see ... heterogenous patterns ... #pathophysiology
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