5 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
TF complexes with ... FXa which itself complexes ... multicomponent complexes ... multicomponent complexes ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... antigen-surface complex ... against these complexes ... or the entire complex ... the complement cascade
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune Complex ... differential #diagnosis #algorithm ... #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... ♀, ↑Age, ESRD Pathophysiology ... complex → plt activation ... • Start non-heparin ... Management #Treatment #Hematology
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
the Coagulation Cascade ... multicomponent complexes ... #Coagulation #Cascade ... diagnosis #models #hematology ... #pathophysiology