21 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... decreased PLT count: CBC ... #Differential # ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Artifact (redo CBC ... • Rheumatic disorders ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Evaluation of Chronic ... Causes of acute ... #Diarrhea #management ... #algorithm #workup ... #diagnosis #differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... MNCD #Dementia #Differential ... #Diagnosis #Geriatrics
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... of re-feeding syndrome ... AKA) — seen in chronic ... #ketones #differential ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... lymphoproliferative disorders ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... blood count with differential
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... Autoimmunity • Chronic ... DDX - Other causes ... : • Nephrotic syndrome ... Malignancies • Chronic
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... the underlying cause ... correction of chronic ... demyelination syndrome ... Diagnosis #Treatment #management