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differential syndrome guillain algorithm aplastic caudaequina chronic common cvid disorders equina fatigue gbs guillainbarre hypogammaglobulinemia immunodeficiency immunology oncology platelet thrombocytopenia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Pulmonary Disease Neurologic
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Campylobacter jejuni - HIV ... Diagnosis: • ... nerve roots and cauda ... #management #treatment ... #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... Differential Diagnosis ... cord infarct • HIV ... cord • Guillain-Barre ... #causes #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... immunodeficiency virus (HIV ... CMV) • Epstein-Barr ... #oncology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... nerve roots and cauda ... #management #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV) ... #diagnosis #management
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