23 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... procedures - Infection ... Risks factor for HIV ... decreased PLT count: CBC ... changes), high MCV anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... Idiopathic • Infections ... - HIV • Immune ... hematology #diagnosis #management
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Polyglandular Autoimmune Syndrome ... • Infectious: ... Disseminated Fungal, HIV ... Surgery, Radiation, Medication ... #endocrinology
Antibiotic Options for Treating MRSA Infections

PO: Doxycycline, Clindamycin, TMP-SMX, Linezolid
IV: Linezolid, Vancomycin, Ceftaroline, Daptomycin, Tigecycline

By Dr.
Treating MRSA Infections ... TMP-SMX, Linezolid IV ... aureus #staph #pharmacology ... #management #microbiology ... #medications
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS
Preventing Bacterial Enteric Illness:
 • Antimicrobial
IDSA Recommendations ... • In rare cases ... Enteric #Bacterial #IDSA ... Prevention #Treatment #management ... #HIVAIDS #pharmacology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... Chemotherapy • Infectious ... : HIV, Hepatitis ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Hematologic • Anemia ... • Malignancy Infectious ... Hepatitis • HIV ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... : TB, fungal infection ... , HIV, adrenoleukodystrophy ... hypophysitis, Sheehan's syndrome ... #Endocrinology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Cytokine Activation Syndrome ... respiratory tract infection ... Siltuximab 11mg/kg IV ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications