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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Campylobacter jejuni - HIV ... #Syndrome #diagnosis ... #management #treatment
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Infectious: HIV ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... Cytomegalovirus, Epstein-Barr ... differential #diagnosis #endocrinology
Causes of Myocarditis
Infectious Etiologies:
 • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... herpesvirus 6, Epstein—Barr ... Hepatitis C virus, HIV ... Immunological Syndromes ... Churg-Strauss syndrome
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Polyglandular Autoimmune Syndrome ... Disseminated Fungal, HIV ... Diagnosis #Algorithm #Causes ... #endocrinology
Causes of Pericarditis - Differential Diagnosis Algorithm
Viral:
 • Coxsackie
 • Echovirus
 • Adenovirus
 • Epstein-Barr virus
Causes of Pericarditis ... Adenovirus • Epstein-Barr ... Cytomegalovirus • HIV ... Post-cardiac injury syndrome ... Diagnosis #Algorithm #Causes
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... elevation • Nausea ... 14%), in which case ... DDX: • Epstein-Barr
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... #Syndrome #diagnosis ... #management #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HIV • Immune ... immunodeficiency virus (HIV ... CMV) • Epstein-Barr ... hematology #diagnosis #management