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diagnosis differential coagulation abnormal causes dermatomyositis management prolonged pt antimda5dm antinxp2 antinxp2dm bleeding bruising cascade classification disease distribution hemostasis hodgkins
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
= Intrinsic = APTT ... Factors 1, 2, 7, 10 Common ... PET #diagnosis #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Disease - Most common ... INR • Normal aPTT ... Disease #Diagnosis #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... deficiency in the common ... inhibitors to the common ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... inhibitors to the common ... #differential #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the face, or the anterior ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
NORMAL PT/NORMAL PTT ... Perform a PTT mixing ... the PT and the PTT ... defects in the common ... Differential #Diagnosis #Hematology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Common Dermatological ... Lichen planus - Wrists ... extremities, flexor wrists ... Trunk, especially anterior ... ; pruritis #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymphoma (HL) is an uncommon ... supraclavicular node • Anterior ... (NSHL) - (most common ... classification #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
the face, or the anterior ... renal carcinoma • Colon ... diagnosis #management #rheumatology ... #dermatology
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