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joint msk oncology pain aplastic apml approach differentiation erythematosus gap globulin lupus monoarthritis monoarticular oligoarthritis polyarthritis polyarticular protein proteingap sle
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... Effusion leukocyte count ... Parvovirus B19 • HIV ... #rheumatology # ... Polyarticular #Oligoarticular
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Send for cell count ... - parvovirus, HIV ... Joint #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... from low blood counts ... #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... • Steroids: IV ... #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... (acute HIV, HBV ... (RA, Temporal arteritis ... gastric tumors • Hematology ... #diagnosis #hematology
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