7 results
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Acute or chronic ... infections related ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Effusion leukocyte count ... Parvovirus B19 • HIV ... Joint #pain #Differential ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Send for cell count ... - parvovirus, HIV ... #rheumatology # ... approach #workup #differential ... #diagnosis #arthritis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... • Steroids: IV ... #management #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Disease (CPPD) Pathophysiology ... concomitant infection ... #Disease #Rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... : • Joint pain ... lymphopenia, low PLT • Anemia ... #Rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... Monosodium urate deposition ... frequent attacks • Arthritis ... concomitant infection ... #rheumatology