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diagnosis allergy rheumatology allergic differential hypersensitivity reactions definitions management vasculitis cryoglobulinemia cryoglobulins erythematosus glomerulonephritis igg4 inflammatory iris large lupus medium
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction Classification ... Type 1 reaction ... 3 reaction: Immune ... complex Type 4 ... Allergic #Reaction #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... (Anaphylaxis) Type ... Ill - Immune Complex-Mediated ... #Classification
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Bowman's space) Immune-Complex ... • Presence of immune ... autoAb against type ... • Minimal immune ... Glomerulonephritis #RPGN #Classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Target: Antigen-Ab immune ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
can activate the immune ... the deposit of immune ... Immune-Mediated ... Types: • Type ... #classification
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
affected, although immune ... can affect any type ... Medium #Large #Classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... surfaces causes an immune ... produced from normal immune ... tissues incites immune ... #Classification
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... reconstituted immune ... Related to the type ... CMV - Retinitis, immune ... weeks for most OI
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• A chronic, immune-mediated ... PATHOPHYSIOLOGY • Immune ... • Pancreas: Type ... complement • Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... context of primary immune
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