10 results
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
TB • LTBI is diagnosed ... result with no clinical ... • History of BCG ... immunocompromised (e.g ... #Workup #TB #Latent
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... surgery, trauma, active ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... production • Actively ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... monoclonality • "Reactive ... Glucocorticoids (0.6 mg/kg ... management #phenotypes #workup ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... inflammatory disease (e.g ... Chemistry profile (e.g ... ANA and RF (if clinical ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... • Malignancy (e.g ... Endocrine disorders (e.g ... #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... Syndrome: • Clinical ... Labs/Diagnosis: ... tissue disorder (e.g ... classification #rheumatology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
oncotic pressures acting ... the Journal of Clinical ... 500 mL in a 70 kg ... phlebotomy/ blood work ... In conclusion, prolonged
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... other pathology (e.g ... Initiate ACEi (short-acting ... , e.g. captopril ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... red bone marrow, e.g ... Diagnosis? ... EMD myeloma Diagnostic ... #Workup #Hematology