11 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology ... #differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
meningococcal, H1N1) Clinical ... Clinical Features ... Electrodiagnostic studies - EMG ... Syndrome #diagnosis #management ... #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... all extremity, facial ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... Syndrome #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... Symptoms #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... - Brain stem/Cranial ... Serologic and EMG ... Gravis #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g ... #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
EMG: LMN Signs in ... conditions listed in differential ... diagnosis column Treatment ... neurons - IV free radical ... neurology #diagnosis #management
Neurosarcoidosis - Diagnosis and Treatment
 • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural
 • Central
Diagnosis and Treatment ... neurosarcoidosis: Clinical ... , Exclusion of Differential ... #management #neurology ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... Clinical Presentation ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g