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diagnosis syndrome neurology rheumatology guillain oncology achalasia activation amyotrophic apml arteritis autoimmune cell dermatology differentiation esophageal essential et gastroenterology gbs
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
complete paralysis of all ... Hands or feet • Pain ... Electrodiagnostic studies - EMG ... Syndrome #diagnosis #management ... #treatment #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... extremity, facial ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... Syndrome #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... - Brain stem/Cranial ... Generalized fatigue - ALS ... Serologic and EMG ... Gravis #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... that worsens as ... Symptoms #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
EMG: LMN Signs in ... conditions listed in differential ... diagnosis column Treatment ... neurons - IV free radical ... neurology #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
atypical chest pain ... • Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... #diagnosis #management
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
saliva • Chest pain ... suggest cancer as ... fibers of the LES (eg ... LES pressure (eg ... Achalasia #diagnosis #management
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