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diagnosis rheumatology management syndrome approach arthritis cell conditions dermatology erythematosus extrarticular lupus msk myopathy myositis neurology oncology person plasmacytoma sapho
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
alterations (e.g ... derangements (e.g ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Hyperparathyroidism • Facial ... disease, Vasculitis (e.g ... #pain #differential ... #diagnosis #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
the result of an autoimmune ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... Endocrine disorders (e.g ... Arthritis: • Joint ... pain • Swan neck
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... substantial muscle pain ... Aldolase levels • EMG ... Syndrome: Fever, joint ... #differential #
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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