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diagnosis rheumatology management arthritis neurology syndrome approach cell conditions dermatology erythematosus extrarticular gravis lupus monoarthritis monoarticular myasthenia myopathy myositis oligoarthritis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
alterations (e.g ... derangements (e.g ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... peripheral vs axial ... #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Hyperparathyroidism • Facial ... disease, Vasculitis (e.g ... #pain #differential ... #diagnosis #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
the result of an autoimmune ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... life-threatening Differential ... - Brain stem/Cranial ... Serologic and EMG
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... Endocrine disorders (e.g ... Arthritis: • Joint ... pain • Swan neck
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... substantial muscle pain ... Aldolase levels • EMG ... Syndrome: Fever, joint ... #differential #
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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