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diagnosis rheumatology arthritis management approach autoimmune cardiology cell conditions dermatology disease erythematosus extrarticular laboratory lupus msk myopathy myositis neurology oncology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
inflammation in persons ... alterations (e.g ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG ... Syndrome Treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Hyperparathyroidism • Facial ... disease, Vasculitis (e.g ... #pain #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... pain • Swan neck
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... healthy elderly persons ... inflammatory disease (e.g ... Chemistry profile (e.g ... , and low back pain
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... exam • 12-lead ECG ... Valvular disease (e.g ... Symptoms: • Chest pain ... /Afib/WPW) • Loss
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... substantial muscle pain ... Aldolase levels • EMG ... : Fever, joint pain ... #differential #
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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