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diagnosis lupus management vasculitis differential systemic antinxp2 antinxp2dm arthritis chronic cll cryoglobulinemia cryoglobulins dermatology dermatomyositis druginduced hematology laboratory leukemia lymphocytic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... : - ANA > ... Evolution: Chronic disease ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Systemic Lupus Erythematosus ... Evolution: Chronic disease ... #comparison #table ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... Systemic lupus erythematosus ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... purpura: strong sign ... SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • Autoimmune diseases ... systemic lupus erythematosus ... diagnosis #types #classification ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... cells can indicate disease ... Leukemia #diagnosis #workup
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... interphalangeal joints ... without increasing CK ... had more severe disease ... diagnosis #management #rheumatology
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