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diagnosis rheumatology treatment hematology hemophagocytic hlh indications infant interstitial lungdisease lymphohistiocytosis macrophage mas pediatrics peds pulmonary sepsis septic septicshock shock
Step by Step Algorithmic Approach to Pediatric Fever Age < 21 days old (or 28 days for
Step by Step Algorithmic ... Age < 21 days old ... Procalcitonin >= 0.5 ng/mL ... Peds #Diagnosis #Management ... #Infant #Fever
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc) Therapeutic indication: absolute decline in FVC >10%
Management of interstitial ... lung disease (ILD ... #lungdisease #ILD ... #indications #management ... #treatment #algorithm
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... cytokines (TNFa,lL1, IL6 ... • Clinical: fever ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... rash) • Heart, lung ... 5000 to 10,000 ng/mL ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... of infection: Lungs ... in any acutely ill ... • Symptoms: Fever ... INITIAL MANAGEMENT
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