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diagnosis management ophthalmology rheumatology bee behcet cns comatose demyelinating disease diseases disorders extraocular gravis headache hearing hematology localization loss monoclonal
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... Young females Differential ... Diagnosis: • CN ... #Pupil #PhysicalExam ... #neurology #ophthalmology
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
Movement Disorders • CN ... Palsy • CN IV ... palsy • CN VI ... #differential # ... diagnosis #ocular
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... Lack of UMN/LMN signs ... #Weakness #Differential ... #Diagnosis #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS
Ptosis - Differential Diagnosis Framework Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... CN III palsy 2. ... junction, cranial nerve ... eyelid: • Third nerve ... #Differential #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... Hypergammaglobulinemic macular ... Evans • ITP • Cl-NH ... Hematology #Monoclonal #Differential
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... nervous system (CNS ... consistent with MS ... #neurology #noninflammatory ... #differential #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... life-threatening Differential ... - Peek sign ... immunologic assay - MuSK ... diagnosis #management #neurology
Photophobia and Headache - Differential Diagnosis Framework Why? • The coexistence of photophobia and headache suggests the potential
meningeal irritation signs ... glaucoma - Ocular ... Trochlear headache • CNS ... the trigeminal nerve ... ophthalmology #Neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... phenomenon (16%) MSK
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