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diagnosis differential hematology hyponatremia nephrology adies cancer hearing leukemia loss monoclonal ophthalmology otolaryngology otology paraproteinemias pupil sodium
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... cirrhosis, nephrotic syndrome ... Pulmonary Diseases ... , CNS Disease, Meds ... #diagnosis #nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... Sneddon-Wilkinson disease ... Differential #Diagnosis #Oncology
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... Diagnosis: • CN ... dissociation • Other causes ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... lysis syndrome: ... #Oncology #Diagnosis
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
include a: • Neurologic ... auditory nerve (CN ... cause unknown) ... II ○ Susac’s syndrome ... ○ HIV ○ Lyme disease
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Differential Diagnosis Algorithm ... capillary leak syndrome ... amyloidosis) • Liver disease ... chemotherapy, nausea ... #nephrology #oncology
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