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management rheumatology erythematosus fungal lupus sle aspergillus autoimmune contagiousness covid19 differential duration ia infectioncontrol infections invasive microbiology mycoses myopathy myositis
Nocardiosis - Nocardia spp Pathogen: Filamentous gram-positive branching rod, grows in acid fast staining and anaerobic conditions Clinical
anaerobic conditions Clinical ... Presentation: • Systemic ... infection 39% • CNS ... 9%, up to 20% lung ... Nocardiosis #Nocardia #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... Aseptic necrosis of hip ... Glomerulonephritis Myositis ... signs #symptoms #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
SOT, Advanced HIV ... /AIDS, CGD) Clinical ... Rhinosinusitis, CNS ... AmphoB or Vori + systemic ... treatment #fungal #infectiousdiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Can cause TYPE IV ... salivary ducts Clinical ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... MALT Lymphoma • Lung
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... and CNS • Headache ... • Transverse Myelitis ... Erythematosus #Diagnosis
Persistence of clinically relevant viruses on dry inanimate surfaces Most common viruses persist on surfaces for days
Persistence of clinically ... virus > 7 days HIV ... A systematic review ... viruses #surfaces #infectiousdiseases ... #diagnosis #table
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN ... • Conduction system
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... especially the CNS ... MC: CNS CSF: • ... change in the lungs ... ) #Mycoses #InfectiousDiseases
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