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differential neurology activation autoimmune behcet cauda caudaequina causes disease equina erythematosus extremity hematology leg lower lupus macrophage mas myopathy myositis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... and diplopia) • Vascular ... #diagnosis #management ... signs #symptoms #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... bouts of HTN Diagnostic ... Diagnosis: • ... negative, MOG-IgG test ... #diagnosis #management
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
- Differential Diagnosis ... Sciatica • Tarsal tunnel ... #differential #diagnosis ... lower #extremity #msk ... #physicalexam
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
(CES) is usually ... • Transverse myelitis ... lumbar stenosis • Vascular ... • Provocative Tests ... absent anal wink test
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... neuropathy, transverse myelitis ... phenomenon (16%) MSK ... #Rheumatology # ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... muscle disease/muscular ... #Myopathy #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
along with (VEGF) vascular ... histopathologic changes in LNs ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
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