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diagnosis differential neurology rheumatology aids hiv infectiousdiseases lung lupus management manifestations neuromyelitis nmo optica pulmonary sle symptoms systemic transverse vasculitis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... • Transverse myelitis ... pain • Extra-CNS ... Systemic lupus erythematosus ... neurology #symptoms #signs
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... Vasculitis • Infectious ... Myeloma/amyloid • Infectious ... Lack of UMN/LMN signs ... Drugs and toxins: Steroids
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Direct microbial infection ... • Bilateral signs ... be ordered • Infectious ... Treatment: • Steroids
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... fibromyalgia) • Infections ... • May involve PNS ... and CNS • Headache ... • Transverse Myelitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... purpura: Strong sign ... ischemia • Skin: Erythematous ... chorioretinitis, CNS ... Cogan syndrome: Ocular
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... papules, pustules, erythematous ... consolidation or nodular ... Lymphadenopathy, CNS
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